靶标：
NCF2
产品别名：
NCF-2； NOXA2； P67-PHOX； P67PHOX； NCF2； neutrophil cytosolic factor 2； neutrophil cytosolic factor 2； neutrophil cytosol factor 2； 67 kDa neutrophil oxidase factor； NADPH oxidase activator 2； chronic granulomatous disease, autosomal 2； neutrophil NADPH oxidase factor 2； neutrophil cytosolic factor 2 (65kD, chronic granulomatous disease, autosomal 2)； NADPH氧化酶活化蛋白1； 嗜中性粒细胞胞浆因子2(NCF2)；
背景信息：
This gene encodes neutrophil cytosolic factor 2, the 67-kilodalton cytosolic subunit of the multi-protein NADPH oxidase complex found in neutrophils. This oxidase produces a burst of superoxide which is delivered to the lumen of the neutrophil phagosome. Mutations in this gene, as well as in other NADPH oxidase subunits, can result in chronic granulomatous disease, a disease that causes recurrent infections by catalase-positive organisms. Alternative splicing results in multiple transcript variants encoding different isoforms.
