靶标：
NDUFS2
产品别名：
CI-49； MC1DN6； NDUFS2； NADH:ubiquinone oxidoreductase core subunit S2； NADH:ubiquinone oxidoreductase core subunit S2； NADH dehydrogenase [ubiquinone] iron-sulfur protein 2, mitochondrial； CI-49kD； NADH dehydrogenase (ubiquinone) Fe-S protein 2, 49kDa (NADH-coenzyme Q reductase)； NADH-ubiquinone oxidoreductase 49 kDa subunit； NADH-ubiquinone oxidoreductase NDUFS2 subunit； complex 1, mitochondrial respiratory chain, 49-KD subunit； complex I 49kDa subunit；
背景信息：
The protein encoded by this gene is a core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (complex I). Mammalian mitochondrial complex I is composed of at least 43 different subunits, 7 of which are encoded by the mitochondrial genome, and the rest are the products of nuclear genes. The iron-sulfur protein fraction of complex I is made up of 7 subunits, including this gene product. Complex I catalyzes the NADH oxidation with concomitant ubiquinone reduction and proton ejection out of the mitochondria. Mutations in this gene are associated with mitochondrial complex I deficiency. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Oct 2009],
