靶标:
NFKBIE
产品别名:
IKBE; NFKBIE; NFKB inhibitor epsilon; NFKB inhibitor epsilon; NF-kappa-B inhibitor epsilon; I-kappa-B-epsilon; NF-kappa-BIE; ikB-E; ikB-epsilon; ikappaBepsilon; nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, epsilon; KB抑制蛋白激酶ε; NF-kappa-B抑制子epsilon;
背景信息:
The protein encoded by this gene binds to components of NF-kappa-B, trapping the complex in the cytoplasm and preventing it from activating genes in the nucleus. Phosphorylation of the encoded protein targets it for destruction by the ubiquitin pathway, which activates NF-kappa-B by making it available to translocate to the nucleus. [provided by RefSeq, Sep 2011],