靶标:
NME3
产品别名:
DR-nm23; NDPK-C; NDPKC; NM23-H3; NM23H3; c371H6.2; NME3; NME/NM23 nucleoside diphosphate kinase 3; NME/NM23 nucleoside diphosphate kinase 3; nucleoside diphosphate kinase 3; NDK 3; NDP kinase 3; NDP kinase C; non-metastatic cells 3, protein expressed in; nucleoside diphosphate kinase C; 二磷酸核苷激酶3; 非转移细胞3表达NM23A蛋白(NME3);
背景信息:
Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate. Probably has a role in normal hematopoiesis by inhibition of granulocyte differentiation and induction of apoptosis.