靶标:
OLR1
产品别名:
CLEC8A; LOX1; LOXIN; SCARE1; SLOX1; OLR1; oxidized low density lipoprotein receptor 1; oxidized low density lipoprotein receptor 1; oxidized low-density lipoprotein receptor 1; C-type lectin domain family 8 member A; hLOX-1; lectin-type oxidized LDL receptor 1; ox LDL receptor 1; oxidized low density lipoprotein (lectin-like) receptor 1; oxidized low-density lipoprotein receptor 1, soluble form; scavenger receptor class E, member 1; 凝集素样氧化低密度脂蛋白受体1(LOX1); 凝集素样氧化型低密度脂蛋白受体; 可溶性凝集素样氧化低密度脂蛋白受体1;
背景信息:
This gene encodes a low density lipoprotein receptor that belongs to the C-type lectin superfamily. This gene is regulated through the cyclic AMP signaling pathway. The encoded protein binds, internalizes and degrades oxidized low-density lipoprotein. This protein may be involved in the regulation of Fas-induced apoptosis. This protein may play a role as a scavenger receptor. Mutations of this gene have been associated with atherosclerosis, risk of myocardial infarction, and may modify the risk of Alzheimer's disease. Alternate splicing results in multiple transcript variants.[provided by RefSeq, Feb 2010],