靶标:
P2RX5
产品别名:
LRH-1; P2X5; P2X5R; P2RX5; purinergic receptor P2X 5; purinergic receptor P2X 5; P2X purinoceptor 5; ATP receptor subunit; ionotropic ATP receptor P2X5; lymphoid-restricted histocompatibility antigen-1; purinergic receptor P2X, ligand gated ion channel, 5; 三磷酸腺苷受体P2X5; 三磷酸腺苷受体P2X5b;
背景信息:
P2X purinoceptor 5 is a protein that in humans is encoded by the P2RX5 gene. The product of this gene belongs to the family of purinoceptors for ATP. It has been identified that the P2RX5 gene within a BAC contig covering chromosome 17p13. This receptor functions as a ligand-gated ion channel. Several characteristic motifs of ATP-gated channels are present in its primary structure, but, unlike other members of the purinoceptors family, this receptor has only a single transmembrane domain. Quantitative dot blots revealed that P2X5R expression is highest in brain and immune system and is developmentally regulated.