靶标:
P2RY2
产品别名:
HP2U; P2RU1; P2U; P2U1; P2UR; P2Y2; P2Y2R; P2RY2; purinergic receptor P2Y2; purinergic receptor P2Y2; P2Y purinoceptor 2; ATP receptor; P2U nucleotide receptor; P2U purinoceptor 1; P2U receptor 1; purinergic receptor P2Y, G-protein coupled, 2; purinoceptor P2Y2; 嘌呤ATP受体; 嘌呤能受体P2Y2(P2RY2);
背景信息:
purinergic receptor P2Y2(P2RY2) Homo sapiens The product of this gene belongs to the family of P2 receptors, which is activated by extracellular nucleotides and subdivided into P2X ligand-gated ion channels and P2Y G-protein coupled receptors. This family has several receptor subtypes with different pharmacological selectivity, which overlaps in some cases, for various adenosine and uridine nucleotides. This receptor, found on many cell types, is activated by ATP and UTP and is reported to be overexpressed on some cancer cell types. It is involved in many cellular functions, such as proliferation, apoptosis and inflammation. Three transcript variants encoding the same protein have been identified for this gene. [provided by RefSeq, Mar 2013],