靶标:
PAEP
产品别名:
GD; GdA; GdF; GdS; PAEG; PEP; PP14; ZIF-1; PAEP; progestagen associated endometrial protein; progestagen associated endometrial protein; glycodelin; PEG; PP14 protein (placental protein 14); alpha uterine protein; glycodelin-A; glycodelin-F; glycodelin-S; placental protein 14; pregnancy-associated endometrial alpha-2 globulin; progestagen-associated endometrial protein (placental protein 14, pregnancy-associated endometrial a; progesterone-associated endometrial protein; zona-binding inhibitory factor-1; β-乳球蛋白; β-乳球蛋白(bLg); 前妊娠蛋白关联子宫内膜蛋白(PAEP); 胎盘蛋白14;
背景信息:
This gene is a member of the kernel lipocalin superfamily whose members share relatively low sequence similarity but have highly conserved exon/intron structure and three-dimensional protein folding. Most lipocalins are clustered on the long arm of chromosome 9. The encoded glycoprotein has been previously referred to as pregnancy-associated endometrial alpha-2-globulin, placental protein 14, and glycodelin, but has been officially named progestagen-associated endometrial protein. Three distinct forms, with identical protein backbones but different glycosylation profiles, are found in amniotic fluid, follicular fluid and seminal plasma of the reproductive system. These glycoproteins have distinct and essential roles in regulating a uterine environment suitable for pregnancy and in the timing and occurrence of the appropriate sequence of events in the fertilization process. Al