靶标：
PAM
产品别名：
PAL； PHM； PAM； peptidylglycine alpha-amidating monooxygenase； peptidylglycine alpha-amidating monooxygenase； peptidyl-glycine alpha-amidating monooxygenase； pancreatic peptidylglycine alpha-amidating monooxygenase； peptidyl alpha-amidating enzyme； peptidyl-alpha-hydroxyglycine alpha-amidating lyase； peptidylamidoglycolate lyase； peptidylglycine 2-hydroxylase； peptidylglycine alpha-hydroxylating monooxygenase； 肽酰甘氨酸2羟化酶； 肽酰甘氨酸α酰胺化单加氧酶(PAM)；
背景信息：
This gene encodes a multifunctional protein. The encoded preproprotein is proteolytically processed to generate the mature enzyme. This enzyme includes two domains with distinct catalytic activities, a peptidylglycine alpha-hydroxylating monooxygenase (PHM) domain and a peptidyl-alpha-hydroxyglycine alpha-amidating lyase (PAL) domain. These catalytic domains work sequentially to catalyze the conversion of neuroendocrine peptides to active alpha-amidated products. Alternative splicing results in multiple transcript variants, at least one of which encodes an isoform that is proteolytically processed. [provided by RefSeq, Jan 2016],
