靶标:
PAX7
产品别名:
HUP1; MYOSCO; PAX7B; RMS2; PAX7; paired box 7; paired box 7; paired box protein Pax-7; PAX7 transcriptional factor; paired box homeotic gene 7; paired domain gene 7; 配对盒基因7;
背景信息:
This gene is a member of the paired box (PAX) family of transcription factors. Members of this gene family typically contain a paired box domain, an octapeptide, and a paired-type homeodomain. These genes play critical roles during fetal development and cancer growth. The specific function of the paired box 7 gene is unknown but speculated to involve tumor suppression since fusion of this gene with a forkhead domain family member has been associated with alveolar rhabdomyosarcoma. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2008],