靶标:
PBX2
产品别名:
G17; HOX12; PBX2MHC; PBX2; PBX homeobox 2; PBX homeobox 2; pre-B-cell leukemia transcription factor 2; XXbac-BPG300A18.13; homeobox 12; homeobox protein PBX2; pre-B-cell leukemia homeobox 2; B淋巴细胞白血病前体蛋白转录因子2;
背景信息:
This gene encodes a ubiquitously expressed member of the TALE/PBX homeobox family. It was identified by its similarity to a homeobox gene which is involved in t(1;19) translocation in acute pre-B-cell leukemias. This protein is a transcriptional activator which binds to the TLX1 promoter. The gene is located within the major histocompatibility complex (MHC) on chromosome 6.