靶标：
PDE1A
产品别名：
CAM-PDE 1A； CAM-PDE-1A； HCAM-1； HCAM1； HSPDE1A； PDE1A； phosphodiesterase 1A； phosphodiesterase 1A； dual specificity calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1A； calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1A； 61 kDa Cam-PDE； calcium/calmodulin-stimulated cyclic nucleotide phosphodiesterase； phosphodiesterase 1A, calmodulin-dependent； 磷酸二酯酶1A； 磷酸二酯酶1A(PDE1A)；
背景信息：
Cyclic nucleotide phosphodiesterases (PDEs) play a role in signal transduction by regulating intracellular cyclic nucleotide concentrations through hydrolysis of cAMP and/or cGMP to their respective nucleoside 5-prime monophosphates. Members of the PDE1 family, such as PDE1A, are Ca(2+)/calmodulin (see CALM1; MIM 114180)-dependent PDEs (CaM-PDEs) that are activated by calmodulin in the presence of Ca(2+) (Michibata et al., 2001 [PubMed 11342109]; Fidock et al., 2002 [PubMed 11747989]).[supplied by OMIM, Oct 2009],
