靶标：
PDE1C
产品别名：
DFNA74； Hcam3； cam-PDE 1C； hCam-3； PDE1C； phosphodiesterase 1C； phosphodiesterase 1C； dual specificity Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1C； calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1C； 3',5'-cyclic-AMP phosphodiesterase； 3',5'-cyclic-GMP phosphodiesterase； Human 3',5' cyclic nucleotide phosphodiesterase (HSPDE1C1A)； phosphodiesterase 1C, calmodulin-dependent 70kDa； 磷酸二酯酶1C； 磷酸二酯酶1C(PDE1C)；
背景信息：
This gene encodes an enzyme that belongs to the 3'5'-cyclic nucleotide phosphodiesterase family. Members of this family catalyze hydrolysis of the cyclic nucleotides, cyclic adenosine monophosphate and cyclic guanosine monophosphate, to the corresponding nucleoside 5'-monophosphates. The enzyme encoded by this gene regulates proliferation and migration of vascular smooth muscle cells, and neointimal hyperplasia. This enzyme also plays a role in pathological vascular remodeling by regulating the stability of growth factor receptors, such as PDGF-receptor-beta.
