靶标:
PDGFA
产品别名:
PDGF-A; PDGF1; PDGFA; platelet derived growth factor subunit A; platelet derived growth factor subunit A; platelet-derived growth factor subunit A; PDGF A-chain; PDGF subunit A; platelet-derived growth factor A-chain; platelet-derived growth factor alpha chain; platelet-derived growth factor alpha polypeptide; 血小板源性生长因子-B; 血小板源性生长因子A; 血小板源性生长因子AA+BB; 血小板源性生长因子AB+BB; 血小板源性生长因子BB; 血小板衍生生长因子A(PDGFA);
背景信息:
platelet derived growth factor subunit A(PDGFA) Homo sapiens This gene encodes a member of the protein family comprised of both platelet-derived growth factors (PDGF) and vascular endothelial growth factors (VEGF). The encoded preproprotein is proteolytically processed to generate platelet-derived growth factor subunit A, which can homodimerize, or alternatively, heterodimerize with the related platelet-derived growth factor subunit B. These proteins bind and activate PDGF receptor tyrosine kinases, which play a role in a wide range of developmental processes. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2015],