靶标:
PDGFRL
产品别名:
PDGRL; PRLTS; PDGFRL; platelet derived growth factor receptor like; platelet derived growth factor receptor like; platelet-derived growth factor receptor-like protein; PDGF receptor beta-like tumor suppressor; PDGFR-like protein; platelet-derived growth factor-beta-like tumor suppressor; 血小板源性生长因子受体β样蛋白; 血小板衍生生长因子受体样蛋白(PDGFRL);
背景信息:
This gene encodes a protein with significant sequence similarity to the ligand binding domain of platelet-derived growth factor receptor beta. Mutations in this gene, or deletion of a chromosomal segment containing this gene, are associated with sporadic hepatocellular carcinomas, colorectal cancers, and non-small cell lung cancers. This suggests this gene product may function as a tumor suppressor. [provided by RefSeq, Jul 2008],