靶标:
PEX14
产品别名:
NAPP2; PBD13A; Pex14p; dJ734G22.2; PEX14; peroxisomal biogenesis factor 14; peroxisomal biogenesis factor 14; peroxisomal membrane protein PEX14; NF-E2 associated polypeptide 2; PTS1 receptor docking protein; peroxin-14; peroxisomal membrane anchor protein PEX14; peroxisomal membrane anchor protein Pex14p; 过氧化物酶体生物合成因子14;
背景信息:
peroxisomal biogenesis factor 14(PEX14) Homo sapiens This gene encodes an essential component of the peroxisomal import machinery. The protein is integrated into peroxisome membranes with its C-terminus exposed to the cytosol, and interacts with the cytosolic receptor for proteins containing a PTS1 peroxisomal targeting signal. The protein also functions as a transcriptional corepressor and interacts with a histone deacetylase. A mutation in this gene results in one form of Zellweger syndrome. [provided by RefSeq, Jul 2008],