靶标:
PGM3
产品别名:
AGM1; IMD23; PAGM; PGM 3; PGM3; phosphoglucomutase 3; phosphoglucomutase 3; phosphoacetylglucosamine mutase; N-acetylglucosamine-phosphate mutase 1; acetylglucosamine phosphomutase;
背景信息:
This gene encodes a member of the phosphohexose mutase family. The encoded protein mediates both glycogen formation and utilization by catalyzing the interconversion of glucose-1-phosphate and glucose-6-phosphate. A non-synonymous single nucleotide polymorphism in this gene may play a role in resistance to diabetic nephropathy and neuropathy. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.