靶标:
PHF1
产品别名:
MTF2L2; PCL1; PHF2; TDRD19C; hPHF1; PHF1; PHD finger protein 1; PHD finger protein 1; PHD finger protein 1; hPCl1; polycomb-like 1; polycomb-like protein 1; testicular tissue protein Li 140; tudor domain containing 19C;
背景信息:
This gene encodes a Polycomb group protein. The protein is a component of a histone H3 lysine-27 (H3K27)-specific methyltransferase complex, and functions in transcriptional repression of homeotic genes. The protein is also recruited to double-strand breaks, and reduced protein levels results in X-ray sensitivity and increased homologous recombination. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May 2009],