靶标：
SERPINI1
产品别名：
HNS-S1； HNS-S2； PI12； neuroserpin； SERPINI1； serpin family I member 1； serpin family I member 1； neuroserpin； PI-12； peptidase inhibitor 12； serine (or cysteine) proteinase inhibitor, clade I (neuroserpin), member 1； serpin I1； serpin peptidase inhibitor clade I member 1； serpin peptidase inhibitor, clade I (neuroserpin), member 1； 丝氨酸或半胱氨酸蛋白水解酶抑制蛋白1； 神经源性丝氨酸蛋白酶抑制剂(NSP)；
背景信息：
This gene encodes a member of the serpin superfamily of serine proteinase inhibitors. The protein is primarily secreted by axons in the brain, and preferentially reacts with and inhibits tissue-type plasminogen activator. It is thought to play a role in the regulation of axonal growth and the development of synaptic plasticity. Mutations in this gene result in familial encephalopathy with neuroserpin inclusion bodies (FENIB), which is a dominantly inherited form of familial encephalopathy and epilepsy characterized by the accumulation of mutant neuroserpin polymers. Multiple alternatively spliced variants, encoding the same protein, have been identified. [provided by RefSeq, Jul 2008],
