靶标:
PKD2
产品别名:
APKD2; PC2; PKD4; Pc-2; TRPP2; PKD2; polycystin 2, transient receptor potential cation channel; polycystin 2, transient receptor potential cation channel; polycystin-2; autosomal dominant polycystic kidney disease type II protein; polycystic kidney disease 2 (autosomal dominant); transient receptor potential cation channel subfamily P member 2; 多囊肾蛋白2;
背景信息:
polycystin 2, transient receptor potential cation channel(PKD2) Homo sapiens This gene encodes a member of the polycystin protein family. The encoded protein is a multi-pass membrane protein that functions as a calcium permeable cation channel, and is involved in calcium transport and calcium signaling in renal epithelial cells. This protein interacts with polycystin 1, and they may be partners in a common signaling cascade involved in tubular morphogenesis. Mutations in this gene are associated with autosomal dominant polycystic kidney disease type 2. [provided by RefSeq, Mar 2011],