靶标：
POLR2E
产品别名：
RPABC1； RPB5； XAP4； hRPB25； hsRPB5； POLR2E； RNA polymerase II, I and III subunit E； RNA polymerase II, I and III subunit E； DNA-directed RNA polymerases I, II, and III subunit RPABC1； DNA directed RNA polymerase II 23 kda polypeptide； DNA-directed RNA polymerase II 23 kDa polypeptide； DNA-directed RNA polymerase II subunit E； DNA-directed RNA polymerase subunit RPABC1； RNA polymerase II subunit E； RNA polymerases I, II, and III subunit ABC1； RPB5 homolog； polymerase (RNA) II (DNA directed) polypeptide E, 25kDa； polymerase (RNA) II subunit E；
背景信息：
This gene encodes the fifth largest subunit of RNA polymerase II, the polymerase responsible for synthesizing messenger RNA in eukaryotes. This subunit is shared by the other two DNA-directed RNA polymerases and is present in two-fold molar excess over the other polymerase subunits. An interaction between this subunit and a hepatitis virus transactivating protein has been demonstrated, suggesting that interaction between transcriptional activators and the polymerase can occur through this subunit. A pseudogene is located on chromosome 11. Three transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Oct 2015],
