靶标:
CTSA
产品别名:
GLB2; GSL; NGBE; PPCA; PPGB; CTSA; cathepsin A; cathepsin A; lysosomal protective protein; beta-galactosidase 2; beta-galactosidase protective protein; carboxypeptidase C; carboxypeptidase Y-like kininase; carboxypeptidase-L; deamidase; lysosomal carboxypeptidase A; protective protein cathepsin A; urinary kininase; 组织蛋白酶A; 组织蛋白酶A(CTSA);
背景信息:
catalytic activity:Release of a C-terminal amino acid with broad specificity.,disease:Defects in CTSA are the cause of galactosialidosis [MIM:256540]. It is an autosomal recessive disease.,function:Protective protein appears to be essential for both the activity of beta-galactosidase and neuraminidase, it associates with these enzymes and exerts a protective function necessary for their stability and activity. This protein is also a carboxypeptidase and can deamidate tachykinins.,similarity:Belongs to the peptidase S10 family.,subunit:Heterodimer of a 32 kDa chain and a 20 kDa chain; disulfide-linked.,