靶标：
PPP2R1B
产品别名：
PP2A-Abeta； PR65B； PPP2R1B； protein phosphatase 2 scaffold subunit Abeta； protein phosphatase 2 scaffold subunit Abeta； serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A beta isoform； protein phosphatase 2, regulatory subunit A, beta； protein phosphatase 2, structural/regulatory subunit A, beta； 蛋白质磷酸酶2调节亚基1B；
背景信息：
This gene encodes a constant regulatory subunit of protein phosphatase 2. Protein phosphatase 2 is one of the four major Ser/Thr phosphatases, and it is implicated in the negative control of cell growth and division. It consists of a common heteromeric core enzyme, which is composed of a catalytic subunit and a constant regulatory subunit, that associates with a variety of regulatory subunits. The constant regulatory subunit A serves as a scaffolding molecule to coordinate the assembly of the catalytic subunit and a variable regulatory B subunit. This gene encodes a beta isoform of the constant regulatory subunit A. Mutations in this gene have been associated with some lung and colon cancers. Alternatively spliced transcript variants have been described. [provided by RefSeq, Apr 2010],
