靶标:
PPP2R3A
产品别名:
PPP2R3; PR130; PR72; PPP2R3A; protein phosphatase 2 regulatory subunit B''alpha; protein phosphatase 2 regulatory subunit B''alpha; serine/threonine-protein phosphatase 2A regulatory subunit B'' subunit alpha; PR130/B''alpha1 subunit; PR72/B''alpha2 subuit; protein phosphatase 2, regulatory subunit B'', alpha; serine/threonine-protein phosphatase 2A 72/130 kDa regulatory subunit B; 蛋白质磷酸酶2A亚基3; 蛋白质磷酸酶2调节亚基3A;
背景信息:
This gene encodes one of the regulatory subunits of the protein phosphatase 2. Protein phosphatase 2 (formerly named type 2A) is one of the four major Ser/Thr phosphatases and is implicated in the negative control of cell growth and division. Protein phosphatase 2 holoenzymes are heterotrimeric proteins composed of a structural subunit A, a catalytic subunit C, and a regulatory subunit B. The regulatory subunit is encoded by a diverse set of genes that have been grouped into the B/PR55, B'/PR61, and B''/PR72 families. These different regulatory subunits confer distinct enzymatic specificities and intracellular localizations to the holozenzyme. The product of this gene belongs to the B'' family. The B'' family has been further divided into subfamilies. The product of this gene belongs to the alpha subfamily of regulatory subunit B&apo