靶标：
PSMA4
产品别名：
HC9； HsT17706； PSC9； PSMA4； proteasome 20S subunit alpha 4； proteasome 20S subunit alpha 4； proteasome subunit alpha type-4； macropain subunit C9； multicatalytic endopeptidase complex subunit C9； proteasome (prosome, macropain) subunit, alpha type, 4； proteasome component C9； proteasome subunit HC9； proteasome subunit L； proteasome subunit alpha 4； proteasome subunit alpha3； 蛋白酶体PSMα4/20S Proteasomeα4；
背景信息：
Proteasome subunit alpha type-4, also known as macropain subunit C9, proteasome component C9, and 20S proteasome subunit alpha-3, is a protein that in humans is encoded by the PSMA4 gene. The proteasome is a multicatalytic proteinase complex with a highly ordered ring-shaped 20S core structure. The core structure is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a member of the peptidase T1A family, that is a 20S core alpha subunit. Three alternatively spliced transcript variants encoding different isoforms have been found for this gene.
