靶标：
PSMD8
产品别名：
HEL-S-91n； HIP6； HYPF； Nin1p； Rpn12； S14； p31； PSMD8； proteasome 26S subunit, non-ATPase 8； proteasome 26S subunit, non-ATPase 8； 26S proteasome non-ATPase regulatory subunit 8； 26S proteasome regulatory subunit RPN12； 26S proteasome regulatory subunit S14； 26S proteasome regulatory subunit p31； epididymis secretory sperm binding protein Li 91n； proteasome (prosome, macropain) 26S subunit, non-ATPase, 8； 蛋白酶调解因子8； 非ATP酶蛋白酶体26S亚基8(PSMD8)；
背景信息：
The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. The 19S regulator is composed of a base, which contains 6 ATPase subunits and 2 non-ATPase subunits, and a lid, which contains up to 10 non-ATPase subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a non-ATPase subunit of the 19S regulator. A pseudogene has been identified on chromosome 1. [provided by RefSeq, Jul 2008],
