靶标:
PTGFR
产品别名:
FP; PTGFR; prostaglandin F receptor; prostaglandin F receptor; prostaglandin F2-alpha receptor; FP prostanoid receptor; PGF receptor; PGF2 alpha receptor; prostaglandin receptor (2-alpha); prostanoid FP receptor; 前列腺素F2a受体PGF2αR;
背景信息:
prostaglandin F receptor(PTGFR) Homo sapiens The protein encoded by this gene is member of the G-protein coupled receptor family. This protein is a receptor for prostaglandin F2-alpha (PGF2-alpha), which is known to be a potent luteolytic agent, and may also be involved in modulating intraocular pressure and smooth muscle contraction in uterus. Knockout studies in mice suggest that the interaction of PGF2-alpha with this receptor may initiate parturition in ovarian luteal cells and thus induce luteolysis. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008],