靶标:
PTPN7
产品别名:
BPTP-4; HEPTP; LC-PTP; LPTP; PTPNI; PTPN7; protein tyrosine phosphatase non-receptor type 7; protein tyrosine phosphatase non-receptor type 7; tyrosine-protein phosphatase non-receptor type 7; dual specificity phosphatase 1; hematopoietic protein-tyrosine phosphatase; protein-tyrosine phosphatase LC-PTP; protein-tyrosine phosphatase, nonreceptor-type, stress induced; 非受体型蛋白酪氨酸磷酸酶7; 非受体型蛋白酪氨酸磷酸酶7(PTPN7);
背景信息:
The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This gene is preferentially expressed in a variety of hematopoietic cells, and is an early response gene in lymphokine stimulated cells. The non-catalytic N-terminus of this PTP can interact with MAP kinases and suppress the MAP kinase activities.