靶标:
PTX3
产品别名:
TNFAIP5; TSG-14; PTX3; pentraxin 3; pentraxin 3; pentraxin-related protein PTX3; TNF alpha-induced protein 5; long pentraxin 3; tumor necrosis factor alpha-induced protein 5; tumor necrosis factor-inducible gene 14 protein; tumor necrosis factor-inducible protein TSG-14; 正五聚蛋白3(PTX3); 肿瘤坏死因子α诱导蛋白5;
背景信息:
This gene encodes a member of the pentraxin protein family. The expression of this protein is induced by inflammatory cytokines in response to inflammatory stimuli in several mesenchymal and epithelial cell types, particularly endothelial cells and mononuclear phagocytes. The protein promotes fibrocyte differentiation and is involved in regulating inflammation and complement activation. It also plays a role in angiogenesis and tissue remodeling. The protein serves as a biomarker for several inflammatory conditions. [provided by RefSeq, Jun 2016],