靶标:
RAD1
产品别名:
HRAD1; REC1; RAD1; RAD1 checkpoint DNA exonuclease; RAD1 checkpoint DNA exonuclease; cell cycle checkpoint protein RAD1; DNA repair exonuclease REC1; DNA repair exonuclease rad1 homolog; RAD1 checkpoint clamp component; RAD1 homolog; cell cycle checkpoint protein Hrad1; checkpoint control protein HRAD1; exonuclease homolog RAD1; rad1-like DNA damage checkpoint protein;
背景信息:
This gene encodes a component of a heterotrimeric cell cycle checkpoint complex, known as the 9-1-1 complex, that is activated to stop cell cycle progression in response to DNA damage or incomplete DNA replication. The 9-1-1 complex is recruited by RAD17 to affected sites where it may attract specialized DNA polymerases and other DNA repair effectors. Alternatively spliced transcript variants of this gene have been described. [provided by RefSeq, Jan 2009],