靶标：
ABCD3
产品别名：
ABC43； CBAS5； PMP70； PXMP1； ZWS2； ABCD3； ATP binding cassette subfamily D member 3； ATP binding cassette subfamily D member 3； ATP-binding cassette sub-family D member 3； 70 kDa peroxisomal membrane protein； ATP-binding cassette, sub-family D (ALD), member 3； Peroxisomal membrane protein-1 (70kD)； dJ824O18.1 (ATP-binding cassette, sub-family D (ALD), member 3 (PMP70, PXMP1))； peroxisomal membrane protein 1 (70kD, Zellweger syndrome)； peroxisomal membrane protein 70 kDa； 过氧化物酶膜蛋白1；
背景信息：
The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the ALD subfamily, which is involved in peroxisomal import of fatty acids and/or fatty acyl-CoAs in the organelle. All known peroxisomal ABC transporters are half transporters which require a partner half transporter molecule to form a functional homodimeric or heterodimeric transporter. This peroxisomal membrane protein likely plays an important role in peroxisome biogenesis. Mutations have been associated with some forms of Zellweger syndrome, a heterogeneous group of peroxisome assembly disorders. Alternative splicing results in multiple transcript variants
