靶标:
RAB2A
产品别名:
LHX; RAB2; RAB2A; RAB2A, member RAS oncogene family; RAB2A, member RAS oncogene family; ras-related protein Rab-2A; RAB2, member RAS oncogene family; small GTP binding protein RAB2A; ras癌基因家族Rab2;
背景信息:
The protein encoded by this gene belongs to the Rab family, members of which are small molecular weight guanosine triphosphatases (GTPases) that contain highly conserved domains involved in GTP binding and hydrolysis. The Rabs are membrane-bound proteins, involved in vesicular fusion and trafficking. This protein is a resident of pre-Golgi intermediates, and is required for protein transport from the endoplasmic reticulum (ER) to the Golgi complex. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2011],