靶标:
RASA2
产品别名:
GAP1M; RASA2; RAS p21 protein activator 2; RAS p21 protein activator 2; ras GTPase-activating protein 2; GTPase-activating protein 1m; GTPase-activating protein of RAS; RAS的GTP酶激活蛋白;
背景信息:
The protein encoded by this gene is member of the GAP1 family of GTPase-activating proteins. The gene product stimulates the GTPase activity of normal RAS p21 but not its oncogenic counterpart. Acting as a suppressor of RAS function, the protein enhances the weak intrinsic GTPase activity of RAS proteins resulting in the inactive GDP-bound form of RAS, thereby allowing control of cellular proliferation and differentiation. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2014],