靶标：
RFC5
产品别名：
RFC36； RFC5； replication factor C subunit 5； replication factor C subunit 5； replication factor C subunit 5； A1 36 kDa subunit； RF-C 36 kDa subunit； RFC, 36.5 kD subunit； replication factor C (activator 1) 5, 36.5kDa； replication factor C, 36-kDa subunit；
背景信息：
The elongation of primed DNA templates by DNA polymerase delta and DNA polymerase epsilon requires the accessory proteins proliferating cell nuclear antigen (PCNA) and replication factor C (RFC). RFC, also named activator 1, is a protein complex consisting of five distinct subunits of 140, 40, 38, 37, and 36 kD. This gene encodes the 36 kD subunit. This subunit can interact with the C-terminal region of PCNA. It forms a core complex with the 38 and 40 kDa subunits. The core complex possesses DNA-dependent ATPase activity, which was found to be stimulated by PCNA in an in vitro system. Alternative splicing results in multiple transcript variants. A related pseudogene has been identified on chromosome 9. [provided by RefSeq, May 2011],
