靶标:
GRK1
产品别名:
GPRK1; RHOK; RK; GRK1; G protein-coupled receptor kinase 1; G protein-coupled receptor kinase 1; rhodopsin kinase GRK1; G蛋白偶合受体激酶1;
背景信息:
This gene encodes a member of the guanine nucleotide-binding protein (G protein)-coupled receptor kinase subfamily of the Ser/Thr protein kinase family. The protein phosphorylates rhodopsin and initiates its deactivation. Defects in GRK1 are known to cause Oguchi disease 2 (also known as stationary night blindness Oguchi type-2). [provided by RefSeq, Jul 2008],