靶标:
RNF4
产品别名:
RES4-26; SLX5; SNURF; RNF4; ring finger protein 4; ring finger protein 4; E3 ubiquitin-protein ligase RNF4; E3 ubiquitin ligase RNF4; RING-type E3 ubiquitin transferase RNF4; small nuclear RING finger protein;
背景信息:
The protein encoded by this gene contains a RING finger motif and acts as a transcription regulator. This protein has been shown to interact with, and inhibit the activity of, TRPS1, a transcription suppressor of GATA-mediated transcription. Transcription repressor ZNF278/PATZ is found to interact with this protein, and thus reduce the enhancement of androgen receptor-dependent transcription mediated by this protein. Studies of the mouse and rat counterparts suggested a role of this protein in spermatogenesis. A pseudogene of this gene is found on chromosome 1.[provided by RefSeq, Jul 2010],