靶标:
RPN1
产品别名:
OST1; RBPH1; RPN1; ribophorin I; ribophorin I; dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1; RPN-I; dolichyl-diphosphooligosaccharide-protein glycosyltransferase 67 kDa subunit; oligosaccharyltransferase 1 homolog; oligosaccharyltransferase complex subunit (non-catalytic); ribophorin-1; 核糖体结合糖蛋白Ⅰ(RPN1);
背景信息:
This gene encodes a type I integral membrane protein found only in the rough endoplasmic reticulum. The encoded protein is part of an N-oligosaccharyl transferase complex that links high mannose oligosaccharides to asparagine residues found in the Asn-X-Ser/Thr consensus motif of nascent polypeptide chains. This protein forms part of the regulatory subunit of the 26S proteasome and may mediate binding of ubiquitin-like domains to this proteasome.