靶标：
SEL1L
产品别名：
Hrd3； PRO1063； SEL1-LIKE； SEL1L1； SEL1L； SEL1L adaptor subunit of ERAD E3 ubiquitin ligase； SEL1L adaptor subunit of ERAD E3 ubiquitin ligase； protein sel-1 homolog 1； SEL1L, ERAD E3 ligase adaptor subunit； Suppressor of lin 12 (sel-1), C. elegans, homolog of； sel-1 suppressor of lin-12-like 1； suppressor of lin-12-like protein 1；
背景信息：
Protein sel-1 homolog 1 is a protein that in humans is encoded by the SEL1L gene. The protein encoded by this gene is part of a protein complex required for the retrotranslocation or dislocation of misfolded proteins from the endoplasmic reticulum lumen to the cytosol, where they are degraded by the proteasome in a ubiquitin-dependent manner. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
