靶标:
SEMA3F
产品别名:
SEMA-IV; SEMA4; SEMAK; SEMA3F; semaphorin 3F; semaphorin 3F; semaphorin-3F; sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3F; sema domain, immunoglobulin domain (Ig), short basic domain, secreted, 3F; semaphorin III/F; semaphorin IV; 信号素3F(SEMA3F); 臂板蛋白3F;
背景信息:
This gene encodes a member of the semaphorin III family of secreted signaling proteins that are involved in axon guidance during neuronal development. The encoded protein contains an N-terminal Sema domain, an immunoglobulin loop and a C-terminal basic domain. This gene is expressed by the endothelial cells where it was found to act in an autocrine fashion to induce apoptosis, inhibit cell proliferation and survival, and function as an anti-tumorigenic agent. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jan 2016],