靶标:
SLC2A2
产品别名:
GLUT2; SLC2A2; solute carrier family 2 member 2; solute carrier family 2 member 2; solute carrier family 2, facilitated glucose transporter member 2; glucose transporter type 2, liver; solute carrier family 2 (facilitated glucose transporter), member 2; 葡萄糖转运蛋白2; 葡萄糖转运蛋白2(GLUT2);
背景信息:
This gene encodes an integral plasma membrane glycoprotein of the liver, islet beta cells, intestine, and kidney epithelium. The encoded protein mediates facilitated bidirectional glucose transport. Because of its low affinity for glucose, it has been suggested as a glucose sensor. Mutations in this gene are associated with susceptibility to diseases, including Fanconi-Bickel syndrome and noninsulin-dependent diabetes mellitus (NIDDM). Alternative splicing results in multiple transcript variants of this gene. [provided by RefSeq, Jul 2013],