靶标:
SLC5A5
产品别名:
NIS; TDH1; SLC5A5; solute carrier family 5 member 5; solute carrier family 5 member 5; sodium/iodide cotransporter; Na(+)/I(-) cotransporter; Na(+)/I(-) symporter; solute carrier family 5 (sodium iodide symporter), member 5; solute carrier family 5 (sodium/iodide cotransporter), member 5; 钠碘转运体蛋白; 钠碘运输蛋白(NIS);
背景信息:
This gene encodes a member of the sodium glucose cotransporter family. The encoded protein is responsible for the uptake of iodine in tissues such as the thyroid and lactating breast tissue. The iodine taken up by the thyroid is incorporated into the metabolic regulators triiodothyronine (T3) and tetraiodothyronine (T4). Mutations in this gene are associated with thyroid dyshormonogenesis 1.[provided by RefSeq, Sep 2009],