靶标:
SLC25A1
产品别名:
CMS23; CTP; D2L2AD; SEA; SLC20A3; SLC25A1; solute carrier family 25 member 1; solute carrier family 25 member 1; tricarboxylate transport protein, mitochondrial; citrate transport protein; solute carrier family 20 (mitochondrial citrate transporter), member 3; solute carrier family 25 (mitochondrial carrier; citrate transporter), member 1; tricarboxylate carrier protein; 溶质载体家族25成员1;
背景信息:
Tricarboxylate transport protein,mitochondrial,also known as tricarboxylate carrier protein and citrate transport protein (CTP),is a protein that in humans is encoded by the SLC25A1 gene. It is mapped to 22q11.21. This gene encodes a member of the mitochondrial carrier subfamily of solute carrier proteins. Members of this family include nuclear-encoded transporters that translocate small metabolites across the mitochondrial membrane. This protein regulates the movement of citrate across the inner membranes of the mitochondria. Mutations in this gene have been associated with combined D-2- and L-2-hydroxyglutaric aciduria. Pseudogenes of this gene have been identified on chromosomes 7,11,16,and 19. Alternative splicing results in multiple transcript variants.