靶标:
SOX4
产品别名:
CSS10; EVI16; SOX4; SRY-box transcription factor 4; SRY-box transcription factor 4; transcription factor SOX-4; SRY (sex determining region Y)-box 4; SRY-box 4; SRY-related HMG-box gene 4; ecotropic viral integration site 16; 核转录因子SOX4;
背景信息:
SRY-box 4(SOX4) Homo sapiens This intronless gene encodes a member of the SOX (SRY-related HMG-box) family of transcription factors involved in the regulation of embryonic development and in the determination of the cell fate. The encoded protein may act as a transcriptional regulator after forming a protein complex with other proteins, such as syndecan binding protein (syntenin). The protein may function in the apoptosis pathway leading to cell death as well as to tumorigenesis and may mediate downstream effects of parathyroid hormone (PTH) and PTH-related protein (PTHrP) in bone development. The solution structure has been resolved for the HMG-box of a similar mouse protein. [provided by RefSeq, Jul 2008],