靶标：
SP100
产品别名：
lysp100b； SP100； SP100 nuclear antigen； SP100 nuclear antigen； nuclear autoantigen Sp-100； SP100-HMG nuclear autoantigen； nuclear dot-associated Sp100 protein； speckled 100 kDa； Sp100核抗原(Sp100)；
背景信息：
This gene encodes a subnuclear organelle and major component of the PML (promyelocytic leukemia)-SP100 nuclear bodies. PML and SP100 are covalently modified by the SUMO-1 modifier, which is considered crucial to nuclear body interactions. The encoded protein binds heterochromatin proteins and is thought to play a role in tumorigenesis, immunity, and gene regulation. Alternatively spliced variants have been identified for this gene; one of which encodes a high-mobility group protein. [provided by RefSeq, Aug 2011],
