靶标：
SPR
产品别名：
SDR38C1； SPR； sepiapterin reductase； sepiapterin reductase； sepiapterin reductase； Sepiapterin reductase (L-erythro-7,8-dihydrobiopterin forming)； sepiapterin reductase (7,8-dihydrobiopterin:NADP+ oxidoreductase)； short chain dehydrogenase/reductase family 38C, member 1； 墨蝶呤还原酶(SPR)； 墨蝶蛉还原酶；
背景信息：
Sepiapterin reductase is an enzyme that in humans is encoded by the SPR gene. This gene encodes an aldo-keto reductase that catalyzes the NADPH-dependent reduction of pteridine derivatives and is important in the biosynthesis of tetrahydrobiopterin (BH4). Mutations in this gene result in DOPA-responsive dystonia due to sepiaterin reductase deficiency. A pseudogene has been identified on chromosome 1.
