靶标：
TBX5
产品别名：
HOS； TBX5； T-box transcription factor 5； T-box transcription factor 5； T-box transcription factor TBX5； T-box 5； T-box protein 5； 转录因子Tbx5；
背景信息：
This gene is a member of a phylogenetically conserved family of genes that share a common DNA-binding domain, the T-box. T-box genes encode transcription factors involved in the regulation of developmental processes. This gene is closely linked to related family member T-box 3 (ulnar mammary syndrome) on human chromosome 12. The encoded protein may play a role in heart development and specification of limb identity. Mutations in this gene have been associated with Holt-Oram syndrome, a developmental disorder affecting the heart and upper limbs. Several transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Jul 2008],
