靶标：
ELOA
产品别名：
SIII； SIII p110； TCEB3； TCEB3A； ELOA； elongin A； elongin A； elongin-A； RNA polymerase II transcription factor SIII subunit A1； elongin 110 kDa subunit； transcription elongation factor B (SIII), polypeptide 3 (110kDa, elongin A)； transcription elongation factor B alpha subunit； transcription elongation factor B polypeptide 3； transcription elongation factor B subunit 3； 延伸蛋白A(ELOA)； 转录延伸因子3/ TCEB3；
背景信息：
This gene encodes the protein elongin A, which is a subunit of the transcription factor B (SIII) complex. The SIII complex is composed of elongins A/A2, B and C. It activates elongation by RNA polymerase II by suppressing transient pausing of the polymerase at many sites within transcription units. Elongin A functions as the transcriptionally active component of the SIII complex, whereas elongins B and C are regulatory subunits. Elongin A2 is specifically expressed in the testis, and capable of forming a stable complex with elongins B and C. The von Hippel-Lindau tumor suppressor protein binds to elongins B and C, and thereby inhibits transcription elongation. [provided by RefSeq, Jul 2008],
