靶标：
VPS72
产品别名：
CFL1； Swc2； TCFL1； YL-1； YL1； VPS72； vacuolar protein sorting 72 homolog； vacuolar protein sorting 72 homolog； vacuolar protein sorting-associated protein 72 homolog； transcription factor-like 1； transformation suppressor gene YL-1； 液泡蛋白分选蛋白72；
背景信息：
The protein encoded by this gene is a shared subunit of two multi-component complexes, the histone acetyltransferase complex TRRAP/TIP60 as well as the chromatin remodeling SRCAP-containing complex. The TRRAP/TIP60 complex acetylates nucleosomal histones important for transcriptional regulation, double strand DNA break repair and apoptosis. The SRCAP-containing complex catalyzes the exchange of histone H2A with the histone variant Htz1 (H2AFZ) into nucleosomes. This protein may be responsible for binding H2AFZ, which has a role in chromosome segregation. This protein may also have a role in regulating long-term hematopoietic stem cell activity. Alternative splicing results in multiple transcript variants that encode different protein isoforms. [provided by RefSeq, Aug 2012],
