靶标:
TFAP4
产品别名:
AP-4; bHLHc41; TFAP4; transcription factor AP-4; transcription factor AP-4; transcription factor AP-4; activating enhancer-binding protein 4; class C basic helix-loop-helix protein 41; transcription factor AP-4 (activating enhancer binding protein 4); 激活增强子结合蛋白4;
背景信息:
Transcription factors of the basic helix-loop-helix-zipper (bHLH-ZIP) family contain a basic domain, which is used for DNA binding, and HLH and ZIP domains, which are used for oligomerization. Transcription factor AP4 activates both viral and cellular genes by binding to the symmetrical DNA sequence CAGCTG (Mermod et al., 1988 [PubMed 2833704]; Hu et al., 1990 [PubMed 2123466]).[supplied by OMIM, Jul 2009]