靶标：
TGM1
产品别名：
ARCI1； ICR2； KTG； LI； LI1； TGASE； TGK； TGM1； transglutaminase 1； transglutaminase 1； protein-glutamine gamma-glutamyltransferase K； K polypeptide epidermal type I, protein-glutamine-gamma-glutamyltransferase； TG(K)； TGase K； TGase-1； epidermal TGase； transglutaminase K； transglutaminase, keratinocyte； 谷氨酰胺转胺酶1； 谷氨酰胺转胺酶1(TGM1)；
背景信息：
The protein encoded by this gene is a membrane protein that catalyzes the addition of an alkyl group from an akylamine to a glutamine residue of a protein, forming an alkylglutamine in the protein. This protein alkylation leads to crosslinking of proteins and catenation of polyamines to proteins. This gene contains either one or two copies of a 22 nt repeat unit in its 3' UTR. Mutations in this gene have been associated with autosomal recessive lamellar ichthyosis (LI) and nonbullous congenital ichthyosiform erythroderma (NCIE).
